Notice
- Important: This guidance is under active development by NHS England and content may be added or updated on a regular basis.
- This Implementation Guide is currently in Draft and SHOULD NOT be used for development or active implementation without express direction from the NHS England Genomics Unit.
Bundle-NonWGSScenario5-ProductsofConception-Example
Example of a Non-WGS test request sent to the central broker, as described in the Clinical Scenario:Fetus Management
Bundle |
id : Bundle-NonWGSScenario5-ProductsofConception-Example |
type : transaction |
entry |
fullUrl : urn:uuid:cf37712a-99c8-495b-9865-a96fffe5133c |
resource |
id : cf37712a-99c8-495b-9865-a96fffe5133c |
identifier |
system : https://fhir.nhs.uk/Id/GMSCompoundIdentifer |
value : RYJ02:https://fhir.nhs.uk/Id/sds-user-id:2441541066 |
practitioner |
identifier |
system : https://fhir.nhs.uk/Id/sds-user-id |
value : 2441541066 |
display : Dr. Lois Lane |
organization |
identifier |
system : https://fhir.nhs.uk/Id/ods-organization-code |
value : RYJ02 |
display : Charing Cross Hospital |
specialty |
coding |
system : https://fhir.hl7.org.uk/CodeSystem/UKCore-PracticeSettingCode |
code : 311 |
display : Clinical Genetics |
telecom |
system : phone |
value : 02085467711 |
telecom |
system : email |
value : Hazel.smith12@nhs.net |
telecom |
extension |
url : http://hl7.org/fhir/StructureDefinition/contactpoint-comment |
value : reporting |
system : email |
value : clinicalgeneticskingston@nhs.net |
telecom |
extension |
url : http://hl7.org/fhir/StructureDefinition/contactpoint-comment |
value : reporting |
system : email |
value : fetalmedicinekingston@nhs.net |
telecom |
extension |
url : http://hl7.org/fhir/StructureDefinition/contactpoint-comment |
value : reporting |
system : email |
value : gptestpracticekingston@nhs.net |
request |
method : POST |
url : PractitionerRole |
entry |
fullUrl : urn:uuid:c60f7e06-79b1-4a34-9979-e8a461b3f7c8 |
resource |
id : c60f7e06-79b1-4a34-9979-e8a461b3f7c8 |
extension |
url : https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-BirthSex |
value |
coding |
system : http://terminology.hl7.org/CodeSystem/v3-AdministrativeGender |
code : F |
display : Female |
extension |
url : https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-EthnicCategory |
value |
coding |
system : https://fhir.hl7.org.uk/CodeSystem/UKCore-EthnicCategoryEngland |
code : A |
display : White - British |
identifier |
extension |
url : https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-NHSNumberVerificationStatus |
value |
coding |
system : https://fhir.hl7.org.uk/CodeSystem/UKCore-NHSNumberVerificationStatusEngland |
version : 1.1.1 |
code : 01 |
display : Number present and verified |
system : https://fhir.nhs.uk/Id/nhs-number |
value : 9449308322 |
identifier |
system : urn:oid:2.16.840.1.113883.2.1.3.2.4.18.24 |
value : 71636034 |
assigner |
identifier |
system : https://fhir.nhs.uk/Id/ods-organization-code |
value : RAX01 |
name |
given : Ryanne |
family : Boulder |
link |
other |
reference : https://int.api.service.nhs.uk/personal-demographics/FHIR/R4/Patient/9449308322 |
type : seealso |
request |
method : POST |
url : Patient |
ifNoneExist : Patient?identifier=https://fhir.nhs.uk/Id/nhs-number|9449308322 |
entry |
fullUrl : urn:uuid:037d8ff3-da35-4fad-9d28-7a120d4fffe9 |
resource |
id : 037d8ff3-da35-4fad-9d28-7a120d4fffe9 |
extension |
url : http://hl7.org/fhir/6.0/StructureDefinition/extension-Patient.fetalStatus |
value : fetal-demise |
identifier |
system : urn:oid:2.16.840.1.113883.2.1.3.2.4.18.24 |
value : FoetusA |
assigner |
identifier |
system : https://fhir.nhs.uk/Id/ods-organization-code |
value : RAX |
name |
family : Fetus A of MUM |
gender : female |
deceased : 2024-05-16T00:00:00-05:00 |
link |
other |
reference : urn:uuid:ac29fd1f-6749-4771-9633-25f39976e48a |
type : RelatedPerson |
type : seealso |
request |
method : POST |
url : Patient |
ifNoneExist : Patient?identifier=urn:oid:2.16.840.1.113883.2.1.3.2.4.18.24|FoetusA |
entry |
fullUrl : urn:uuid:a0684de7-7cf5-43a3-b3ba-3dd13e4c2f4f |
resource |
id : a0684de7-7cf5-43a3-b3ba-3dd13e4c2f4f |
status : final |
code |
coding |
system : http://snomed.info/sct |
code : 723621000000103 |
display : Ethnicity |
subject |
reference : urn:uuid:c60f7e06-79b1-4a34-9979-e8a461b3f7c8 |
type : Patient |
identifier |
system : https://fhir.nhs.uk/Id/nhs-number |
value : 9449308322 |
value : unknown |
request |
method : POST |
url : Observation |
entry |
fullUrl : urn:uuid:a5838f88-99af-4ef9-bcb6-150781680d4d |
resource |
id : a5838f88-99af-4ef9-bcb6-150781680d4d |
extension |
url : https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-Coverage |
value |
coding |
system : https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory |
code : nhs-england |
display : NHS England |
identifier |
system : https://fhir.nhs.uk/Id/GMSOrder |
value : 5562279a-bb88-45ef-8fbc-b62c09fbbdb2 |
basedOn |
reference : ServieRequest/ServiceRequest-NonWGSTestOrderForm-UsingStoredSample-Example |
status : active |
intent : order |
category |
coding |
system : https://fhir.hl7.org.uk/CodeSystem/UKCore-GenomeSequencingCategory |
code : rare-disease-non-wgs |
display : Rare Disease - Non-WGS |
priority : urgent |
code |
coding |
system : https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory |
version : 7 |
code : R21.1 |
display : Fetal anomalies with a likely genetic cause |
subject |
reference : urn:uuid:c60f7e06-79b1-4a34-9979-e8a461b3f7c8 |
type : Patient |
identifier |
system : https://fhir.nhs.uk/Id/nhs-number |
value : 9449308322 |
authoredOn : 2025-09-05 |
requester |
reference : urn:uuid:cf37712a-99c8-495b-9865-a96fffe5133c |
type : PractitionerRole |
identifier |
system : https://fhir.nhs.uk/Id/ods-organization-code |
value : RYJ02 |
performer |
identifier |
system : https://fhir.nhs.uk/Id/ods-organization-code |
value : 699N0 |
reasonCode |
coding |
system : https://fhir.nhs.uk/CodeSystem/reasonfortesting-genomics |
code : staging-or-prognosis |
display : Staging or Prognosis |
supportingInfo |
reference : urn:uuid:3e58d52e-aff3-4a70-956b-28509c664f59 |
type : Observation |
supportingInfo |
reference : urn:uuid:193e30bd-6827-468d-b9b7-0849278305db |
type : Observation |
supportingInfo |
reference : urn:uuid:a0684de7-7cf5-43a3-b3ba-3dd13e4c2f4f |
type : Observation |
supportingInfo |
reference : urn:uuid:554cddd5-7b36-4931-aef2-e96c7fc1f322 |
type : Observation |
supportingInfo |
reference : urn:uuid:e8f9a82e-4a01-4449-9c80-c4d38090884f |
type : Observation |
supportingInfo |
reference : urn:uuid:e1858a31-b153-4525-83d6-805cb682df28 |
type : Observation |
supportingInfo |
reference : urn:uuid:5398e192-d44a-4e07-9cdb-63cdeb4ed47a |
type : Observation |
supportingInfo |
reference : urn:uuid:fe049bb9-7988-4209-a5a7-364f7829950d |
type : Procedure |
supportingInfo |
reference : urn:uuid:ac29fd1f-6749-4771-9633-25f39976e48a |
type : RelatedPerson |
supportingInfo |
reference : urn:uuid:037d8ff3-da35-4fad-9d28-7a120d4fffe9 |
type : Patient |
specimen |
reference : urn:uuid:6c83fb14-0eb9-465b-8d2c-062b03b12371 |
type : Specimen |
note |
text : Samples are to be provided at a later date |
note |
text : No family history of relevant testing |
note |
text : Free text for diagnosis/reason for referral, relevant information including family history, phenotypic details/ HPO Terms/ E.g. large echogenic kidneys with normal bladder |
request |
method : POST |
url : ServiceRequest |
entry |
fullUrl : urn:uuid:3e58d52e-aff3-4a70-956b-28509c664f59 |
resource |
id : 3e58d52e-aff3-4a70-956b-28509c664f59 |
status : final |
category |
coding |
system : http://terminology.hl7.org/CodeSystem/observation-category |
code : social-history |
display : Social History |
code |
coding |
system : http://snomed.info/sct |
code : 267013003 |
display : Past pregnancy outcome |
text : Outcome of pregnancy |
subject |
reference : urn:uuid:c60f7e06-79b1-4a34-9979-e8a461b3f7c8 |
type : Patient |
identifier |
system : https://fhir.nhs.uk/Id/nhs-number |
value : 9449308322 |
effective : 2025-08-25 |
value |
coding |
system : http://snomed.info/sct |
code : 237365001 |
display : Fresh stillbirth |
text : a fetal death occurring at or after 28 weeks of pregnancy |
request |
method : POST |
url : Observation |
entry |
fullUrl : urn:uuid:554cddd5-7b36-4931-aef2-e96c7fc1f322 |
resource |
id : 554cddd5-7b36-4931-aef2-e96c7fc1f322 |
status : final |
code |
coding |
system : http://snomed.info/sct |
code : 77386006 |
display : Pregnancy |
subject |
reference : urn:uuid:c60f7e06-79b1-4a34-9979-e8a461b3f7c8 |
type : Patient |
identifier |
system : https://fhir.nhs.uk/Id/nhs-number |
value : 9449308322 |
effective : 2025-08-25 |
component |
code |
coding |
system : http://snomed.info/sct |
code : 720451000000102 |
display : Assisted conception |
component |
code |
coding |
system : http://snomed.info/sct |
code : 226081000000107 |
display : Gestational age |
value |
value : 87 |
unit : day |
system : http://unitsofmeasure.org |
code : d |
component |
code |
coding |
system : http://snomed.info/sct |
code : 161714006 |
display : Estimated date of delivery |
value : 2025-08-25 |
request |
method : POST |
url : Observation |
entry |
fullUrl : urn:uuid:193e30bd-6827-468d-b9b7-0849278305db |
resource |
id : 193e30bd-6827-468d-b9b7-0849278305db |
status : final |
code |
coding |
system : http://snomed.info/sct |
code : 160475008 |
display : Family history of consanguinity |
subject |
reference : urn:uuid:037d8ff3-da35-4fad-9d28-7a120d4fffe9 |
type : Patient |
effective : 2025-08-25 |
value : False |
request |
method : POST |
url : Observation |
entry |
fullUrl : urn:uuid:e8f9a82e-4a01-4449-9c80-c4d38090884f |
resource |
id : e8f9a82e-4a01-4449-9c80-c4d38090884f |
status : final |
code |
coding |
system : http://snomed.info/sct |
code : 416128008 |
display : No history of procedure |
subject |
reference : urn:uuid:c60f7e06-79b1-4a34-9979-e8a461b3f7c8 |
type : Patient |
identifier |
system : https://fhir.nhs.uk/Id/nhs-number |
value : 9449308322 |
effective : 2025-08-25 |
value |
coding |
system : http://snomed.info/sct |
code : 263903005 |
display : Transplant |
request |
method : POST |
url : Observation |
entry |
fullUrl : urn:uuid:e1858a31-b153-4525-83d6-805cb682df28 |
resource |
id : e1858a31-b153-4525-83d6-805cb682df28 |
status : final |
code |
coding |
system : http://snomed.info/sct |
code : 609520005 |
display : Disorder of fetal structure |
text : First Trimester Anomalies? |
subject |
reference : urn:uuid:c60f7e06-79b1-4a34-9979-e8a461b3f7c8 |
type : Patient |
identifier |
system : https://fhir.nhs.uk/Id/nhs-number |
value : 9449308322 |
effective : 2025-08-25 |
value : False |
component |
code |
coding |
system : http://snomed.info/sct |
code : 255246003 |
display : First trimester |
request |
method : POST |
url : Observation |
entry |
fullUrl : urn:uuid:5398e192-d44a-4e07-9cdb-63cdeb4ed47a |
resource |
id : 5398e192-d44a-4e07-9cdb-63cdeb4ed47a |
status : final |
code |
coding |
system : http://snomed.info/sct |
code : 609520005 |
display : Disorder of fetal structure |
text : Second Trimester Anomalies? |
subject |
reference : urn:uuid:c60f7e06-79b1-4a34-9979-e8a461b3f7c8 |
type : Patient |
identifier |
system : https://fhir.nhs.uk/Id/nhs-number |
value : 9449308322 |
effective : 2025-08-25 |
value : False |
component |
code |
coding |
system : http://snomed.info/sct |
code : 255247007 |
display : Second trimester |
request |
method : POST |
url : Observation |
entry |
fullUrl : urn:uuid:fe049bb9-7988-4209-a5a7-364f7829950d |
resource |
id : fe049bb9-7988-4209-a5a7-364f7829950d |
status : completed |
code |
coding |
system : http://snomed.info/sct |
code : 52637005 |
display : In vitro fertilisation |
subject |
reference : urn:uuid:c60f7e06-79b1-4a34-9979-e8a461b3f7c8 |
type : Patient |
identifier |
system : https://fhir.nhs.uk/Id/nhs-number |
value : 9449308322 |
performed : 2025-05-25 |
note |
text : Woman`s own egg |
request |
method : POST |
url : Procedure |
entry |
fullUrl : urn:uuid:6c83fb14-0eb9-465b-8d2c-062b03b12371 |
resource |
id : 6c83fb14-0eb9-465b-8d2c-062b03b12371 |
meta |
tag |
system : https://fhir.hl7.org.uk/CodeSystem/UKCore-FundingCategory |
code : nhs-england |
display : NHS England |
identifier |
system : https://fhir.add.nhs.uk/Id/specimenId |
value : RGT19427897 |
status : unavailable |
type |
coding |
system : http://snomed.info/sct |
code : 258565009 |
display : Chorionic villi specimen |
subject |
reference : urn:uuid:037d8ff3-da35-4fad-9d28-7a120d4fffe9 |
type : Patient |
request |
reference : ServieRequest/ServiceRequest-NonWGSTestOrderForm-UsingStoredSample-Example |
type : ServiceRequest |
request |
method : POST |
url : Specimen |
entry |
fullUrl : urn:uuid:ac29fd1f-6749-4771-9633-25f39976e48a |
resource |
id : ac29fd1f-6749-4771-9633-25f39976e48a |
identifier |
system : urn:oid:2.16.840.1.113883.2.1.3.2.4.18.24 |
value : 6988036185 |
assigner |
identifier |
system : https://fhir.nhs.uk/Id/ods-organization-code |
value : RAX |
patient |
reference : urn:uuid:c60f7e06-79b1-4a34-9979-e8a461b3f7c8 |
type : Patient |
identifier |
system : https://fhir.nhs.uk/Id/nhs-number |
value : 9449308322 |
relationship |
coding |
system : http://terminology.hl7.org/CodeSystem/v3-RoleCode |
code : NCHILD |
display : natural child |
request |
method : POST |
url : RelatedPerson |
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<PractitionerRole>
</identifier>
</identifier>
</practitioner>
</identifier>
</organization>
</coding>
</specialty>
</telecom>
</telecom>
</extension>
</telecom>
</extension>
</telecom>
</extension>
</telecom>
</PractitionerRole>
</resource>
</request>
</entry>
<Patient>
</coding>
</valueCodeableConcept>
</extension>
</coding>
</valueCodeableConcept>
</extension>
<extension url="https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-NHSNumberVerificationStatus">
</coding>
</valueCodeableConcept>
</extension>
</identifier>
</identifier>
</assigner>
</identifier>
</name>
<reference value="https://int.api.service.nhs.uk/personal-demographics/FHIR/R4/Patient/9449308322" />
</other>
</link>
</Patient>
</resource>
</request>
</entry>
<Patient>
</extension>
</identifier>
</assigner>
</identifier>
</name>
</other>
</link>
</Patient>
</resource>
</request>
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<Observation>
</coding>
</code>
</identifier>
</subject>
</Observation>
</resource>
</request>
</entry>
<ServiceRequest>
</coding>
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</extension>
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</coding>
</category>
</coding>
</code>
</identifier>
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</requester>
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</performer>
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</reasonCode>
</supportingInfo>
</supportingInfo>
</supportingInfo>
</supportingInfo>
</supportingInfo>
</supportingInfo>
</supportingInfo>
</supportingInfo>
</supportingInfo>
</supportingInfo>
</specimen>
</note>
</note>
<text value="Free text for diagnosis/reason for referral, relevant information including family history, phenotypic details/ HPO Terms/ E.g. large echogenic kidneys with normal bladder" />
</note>
</ServiceRequest>
</resource>
</request>
</entry>
<Observation>
</coding>
</category>
</coding>
</code>
</identifier>
</subject>
</coding>
</valueCodeableConcept>
</Observation>
</resource>
</request>
</entry>
<Observation>
</coding>
</code>
</identifier>
</subject>
</coding>
</code>
</component>
</coding>
</code>
</valueQuantity>
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</coding>
</code>
</component>
</Observation>
</resource>
</request>
</entry>
<Observation>
</coding>
</code>
</subject>
</Observation>
</resource>
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<Observation>
</coding>
</code>
</identifier>
</subject>
</coding>
</valueCodeableConcept>
</Observation>
</resource>
</request>
</entry>
<Observation>
</coding>
</code>
</identifier>
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</coding>
</code>
</component>
</Observation>
</resource>
</request>
</entry>
<Observation>
</coding>
</code>
</identifier>
</subject>
</coding>
</code>
</component>
</Observation>
</resource>
</request>
</entry>
<Procedure>
</coding>
</code>
</identifier>
</subject>
</note>
</Procedure>
</resource>
</request>
</entry>
<Specimen>
</tag>
</meta>
</identifier>
</coding>
</type>
</subject>
</request>
</Specimen>
</resource>
</request>
</entry>
<RelatedPerson>
</identifier>
</assigner>
</identifier>
</identifier>
</patient>
</coding>
</relationship>
</RelatedPerson>
</resource>
</request>
</entry>
</Bundle>